Possible Link Between Accutane and Celiac Disease

Lance Andrews | March 2nd, 2011 | Posted in Accutane Lawsuit News


Link to Original Press Artricle: http://accutanelawsuit-info.com/2011/03/possible-link-between-accutane-celiac-disease/

The list of Accutane side effects is fairly established since the drug has been in use since the early 1980s, but a new study indicates that a connection between Accutane and celiac disease could exist. Accutane is already linked to several severe and potentially life threatening side effects. These Accutane side effects include: birth defects, suicide, depression,inflammatory bowel disease, Crohn’s Disease, hair loss, cholesterol level increases, increased blood fat levels and dry lips, mouth or nose.

Study says Accutane by-products may cause immune response and celiac symptoms

Findings that were recently published in the scientific journal Nature resulting from a study by University of Chicago’s Digestive Disease Research Core Center researchers indicated that Accutane byproducts, Vitamin A and retinoic acid, may cause inflammation in people with high levels of interleukin-15. This can result in digestive problems whenever this individual eats wheat gluten (commonly found in cereal, pasta, etc.)

This unusual immune response to gluten is referred to as celiac disease. celiac disease affects approximately 1% of the population.

Celiac disease symptoms in Accutane users can include:

  • Fatigue
  • Anemia
  • Bone problems
  • Weight loss

Researchers involved in the study on Accutane celiac disease connections are theorizing that high levels of interleukin-15 may be a key to further researching food allergies in general. blocking the production of interleukin-15 in mice resulted in the mice’s toleration of the gluten.

This research indicates that an additional serious side effect may be added to the established list of Accutane side effects. Since its introduction in the1980s, Accutane has been used by over 16 million people in over 80 countries. While it was approved by the FDA as a treatment for severe acne, it was commonly prescribed as a treatment for all acne ranging from mild to severe. Roche discontinued Accutane in response to litigation costs in 2009. But generic forms of the drug are still available.